All of these over-the-counter medicines, to a varying degree, can relieve the symptoms of heartburn if you have more severe heartburn symptoms that these medications don't relieve, or if you've. Gerd over the counter medicine. Antacids popular over-the-counter medications like tums, maalox, rolaids and mylanta neutralize stomach acid and provide fast-acting relief in mild or isolated cases of acid reflux.
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